During 2021, securities case filings fell for the second consecutive year and, for the first time since 2016, fewer than 300 federal securities class actions were filed. Despite the ongoing pandemic, the number of announced settlements of securities cases was up substantially in 2021, with 116 approved monetary class action settlements totaling $3.5 billion. The 2021 settlements include one mega-settlement of more than $1 billion and a number of other large settlements. Case filings involving COVID-19, SPACs, and cryptocurrencies continued to trend upward in 2021, and we address important developments relating to securities litigation in those sectors.