On August 14, 2015, the Department of Energy's (DOE) BioEnergy Science Center (BESC) announced the creation of a microbe that increases isobutanol yields by a factor of ten. The study, published in Metabolic Engineering, expanded upon a 2011 study where researchers were able to engineer genetically a microbe to produce isobutanol directly from cellulose. The new study used a higher yielding microbe with similar engineered traits, resulting in consolidated bioprocessing efficiency. This progress towards the commercialization of biobased isobutanol is important because its energy density and octane values are close to those of gasoline, allowing it to be used as either a direct replacement for gasoline or a chemical feedstock for a wide range of products.

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