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FDA issues 3-year exclusivity draft guidance clarifying requirements to obtain exclusivity and providing model language for...

On March 3, 2026, the U.S. Food and Drug Administration (FDA) announced the publication of its new draft guidance “New Clinical Investigation Exclusivity (3-Year Exclusivity) for Drug Products: Questions and Answers” ("NCIE...more

Pharma and biotech innovation and competition in 2026: Five areas to watch

FDA has undergone fundamental changes under the Trump administration. The agency is smaller, but is it smarter? Commissioner Makary has embraced AI and appears to be looking for new ways to abbreviate clinical development for...more

Latest congressional spending package includes important updates for orphan disease and pediatric drug development

On February 3, 2026, President Trump signed into law the Mikaela Naylon Give Kids A Chance Act as part of the Consolidated Appropriations Act (CAA) of 2026. The CAA codifies FDA's interpretation of the scope of orphan drug...more

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