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CDER Director Dr. Pazdur to Retire, Dr. Høeg Named as Replacement and Other CDER Leadership Changes, the U.S. House of...

Through our Venable FDA Pulse series, we provide insight into key developments within the Food and Drug Administration (FDA or the Agency), emerging trends, enforcement activity, and other topics impacting stakeholders. ...more

Prepare for FDA Proposal to Require Mandatory GRAS Notices

On December 1, the U.S. Food and Drug Administration (FDA) sent its proposed Generally Recognized as Safe (GRAS) rule, which is expected to mandate submission of GRAS notices for human and animal food substances, to the...more

FDA Announces Seizure of 7-Hydroxymitragynine Products in Missouri

On December 2, 2025, the FDA, with the Department of Justice and U.S. Marshals Service, seized approximately 73,000 units of 7-hydroxymitragynine (7-OH) products from three Missouri firms. ...more

FDA Leaders Outline New “Plausible Mechanism Pathway,” the Agency’s Plans to Hire More Staff, and a Pilot Aimed at Faster Meeting...

Through our Venable FDA Pulse series, we provide insight into key developments within the Food and Drug Administration (FDA or the Agency), emerging trends, enforcement activity, and other topics impacting stakeholders....more

EPA Proposes Major Changes to TSCA § 8(a)(7) PFAS Reporting Rule

On October 11, 2023, the United States Environmental Protection Agency (EPA) promulgated a final rule pursuant to section 8(a)(7) of the Toxic Substances Control Act (TSCA) imposing a one-time reporting obligation on entities...more

Dr. Pazdur in at CDER, Leadership Developments in Key FDA Offices, and FDA Announces Reforms to Accelerate Biosimilars

Through our Venable FDA Pulse series, we provide insight into key developments within the Food and Drug Administration (FDA or the Agency), emerging trends, enforcement activity, and other topics impacting stakeholders....more

Federal Funding Bill Overhauls Hemp Definition, THC Cap

The President signed into law the government funding package that includes a sweeping amendment redefining “hemp” and imposing a 0.4 mg total THC limit per finished product. ...more

Dr. Tidmarsh Resigns as Director of CDER, Leadership Developments in Key FDA Offices, and FDA Announces Reforms to Accelerate...

Through our Venable FDA Pulse series, we provide insight into key developments within the Food and Drug Administration (FDA or the Agency), emerging trends, enforcement activity, and other topics impacting stakeholders. ...more

States Extended Producer Responsibility (EPR) Laws: What Companies Need to Know Now

As of October of this year, seven states have passed EPR laws (i.e., California, Colorado, Maine, Maryland, Minnesota, Oregon, and Washington), and more have bills pending in their legislatures. These laws are intended to...more

Shutdown Updates, FDA Orphan Drug Leader Reassigned as CMS Issues Orphan Drugs Guidance, FDA to Host Allergen Threshold Meeting,...

Through our Venable FDA Pulse series, we provide insight into key developments within the Food and Drug Administration (FDA or the Agency), emerging trends, enforcement activity, and other topics impacting stakeholders....more

Impact of the Government Shutdown on FDA, New ANDA Prioritization Pilot Program, and FDA Holds PreCheck Meeting with Stakeholders

Through our Venable FDA Pulse series, we provide insight into key developments within the Food and Drug Administration (FDA or the Agency), emerging trends, enforcement activity, and other topics impacting stakeholders....more

FDA Declares Nicotinamide Mononucleotide Is a Dietary Supplement

On Monday, the U.S. Food and Drug Administration (FDA or the Agency) responded to a citizen petition about beta nicotinamide mononucleotide (NMN), signaling a shift in its regulatory approach that brings both opportunities...more

FDA Announces Autism-Related Initiatives, Malaria Guidance, CBER Leadership, Pediatric Voucher Bill, and LDT Rule Rescinded

Through our Venable FDA Pulse series, we report on critical developments within the Food and Drug Administration (FDA or Agency) that may affect the Agency's structure and stakeholder interactions. ...more

FDA Announces Notice of Proposed Rulemaking to Eliminate Self-Affirmed GRAS and Revise GRAS Review Criteria

Last week, the Office of Information and Regulatory Affairs released the spring 2025 edition of the Unified Agenda of Federal Regulatory and Deregulatory Actions (Unified Agenda). This semiannual publication outlines the...more

The End of FDA’s LDT Rule, Trump Administration’s Regulatory Agenda Released, an Analysis of HHS Workforce Reductions Raises...

Earlier this month, the Office of Information and Regulatory Affairs (OIRA) updated its list of rules pending review under Executive Order 12866 to include FDA's request to rescind its controversial Laboratory Develop Test...more

Is Trouble Brewing for Dietary Ingredients? Court Upholds NYC Kava Ban

The U.S. District Court for the Southern District of New York recently upheld New York City's prohibition on steeped kava beverages, concluding that steeping kava root in water constitutes the creation of an unapproved "food...more

FDA Announces Plan to Restrict 7-OH Opioid Products

On July 29, 2025, during a joint press conference, the U.S. Food and Drug Administration (FDA or the Agency) recommended to the Drug Enforcement Administration (DEA) to classify 7-hydroxymitragynine (7-OH) as a Schedule I...more

The Return of CBER Director Prasad, FDA Announces New Chief Counsel, and FDA Budget Watch

In our Venable FDA Pulse series, we report on critical developments within the Food and Drug Administration (FDA or the Agency) that may affect the Agency′s structure and stakeholder interactions. ...more

HHS Finalizes Staffing Cuts, New CDER Director, CDER Hiring Data, and New AI Councils at FDA

Through our Venable FDA Pulse series, we report on critical developments within the Food and Drug Administration (FDA or Agency) that may affect the Agency's structure and stakeholder interactions....more

Venable FDA Pulse: FDA at the 100-Day Mark of Trump Administration 2.0

Since returning to office for a second term, President Trump has taken steps to reshape federal agencies. Here, we discuss the significant changes that have occurred at the Food and Drug Administration (FDA or Agency) during...more

FDA to Phase Out Eight Artificial Dyes by 2026

On April 22, 2025, the U.S. Department of Health and Human Services and the U.S. Food and Drug Administration announced a series of new measures to quickly phase out all petroleum-based synthetic dyes from the nation’s food...more

Food Industry Braces Itself as FDA Announces Plan to Ban Artificial Dyes

On April 21, 2025, it was reported that the U.S. Department of Health and Human Services (HHS) has released a media advisory describing the Food and Drug Administration’s (FDA) intention to remove petroleum-based synthetic...more

Exploring the Future of GRAS: HHS’s Recent Directive and Its Potential Impact on the Food Industry

On March 10, 2025, the U.S. Department of Health and Human Services (HHS) announced that HHS Secretary Robert F. Kennedy has directed the Food and Drug Administration (FDA or Agency) “to take steps to explore potential...more

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