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FDA Approval Regulatory Oversight

McGuireWoods LLP

FDA’s PreCheck Pilot Program: What Manufacturers and Investors Need to Know

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On Feb. 1, 2026, the FDA officially launched its Manufacturing PreCheck Pilot Program, which is intended to de-risk and accelerate the establishment of U.S. pharmaceutical manufacturing facilities by increasing regulatory...more

Alston & Bird

Biological Products Regulation Part 5: Preparing for the FDA’s Pre-License Inspection

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Welcome to Alston & Bird’s introduction to biological products regulation. In this five-part intro-level series, we provide answers to a number of questions drug developers may have about the regulation and regulatory pathway...more

ArentFox Schiff

The Eyes Have It: FDA Approves Phase 1 Clinical Trial of Life Biosciences’ Reprogramming Therapy for Vision Loss

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The US Food and Drug Administration (FDA) has approved a Phase 1 clinical trial from Life Biosciences that aims to help certain eye cells act younger and improve vision in glaucoma and related conditions....more

Robins Kaplan LLP

Generic Launches - Fourth Quarter 2025

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This chart tracks the date, drug, reference-listed company, applicant, and indications of publicly available drug launches resulting from Abbreviated New Drug Applications and 505(b)(2) Applications....more

Bass, Berry & Sims PLC

Preventative Care Test Garners Commercial Cost-Sharing Waiver Flexibility from OIG

Bass, Berry & Sims PLC on

On January 16, the U.S. Department of Health and Human Services Office of Inspector General (OIG) published Advisory Opinion 26-01, approving a proposal by the manufacturer of a clinical laboratory test used to screen for...more

Robins Kaplan LLP

ANDA Approvals - Fourth Quarter 2025

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This chart tracks the date, drug, reference-listed company, and applicant of Abbreviated New Drug Applications and 505(b)(2) Applications receiving final approval by the FDA....more

Alston & Bird

Biological Products Regulation Part 3: Unlocking Reference Product Exclusivity: What Sponsors Need to Know

Alston & Bird on

Welcome to Alston & Bird’s introduction to biological products regulation. In this five-part intro-level series, we provide answers to a number of questions drug developers may have about the regulation and regulatory pathway...more

Skadden, Arps, Slate, Meagher & Flom LLP

New FDA Approach to Drug Prices Adds Uncertainty to Drug Approval Process

In the first year of the second Trump administration, we have seen the Food and Drug Administration (FDA) take an unprecedented role in drug pricing policy....more

Venable LLP

Denosumab Biosimilar Updates: Boncresa™ / Oziltus™ Approval, AVT03 Complete Response Letter

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On December 19, 2025, the FDA approved Amneal / mAbxience’s Boncresa™ / Oziltus™ (denosumab-mobz) as the nineth biosimilars of Amgen’s Prolia® / Xgeva® (denosumab). ...more

Vicente LLP

The Legality of Distributing and Dispensing Botanical Cannabis under Schedule III

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In this collaborative analysis, Vicente LLP and the preeminent FDA law firm Kleinfeld, Kaplan & Becker LLP examine how the potential reclassification of cannabis into Schedule III could impact its distribution and dispensing....more

Jones Day

FDA Drives Digital Health Forward With Pilot Program for Chronic Condition Devices

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A new Food and Drug Administration ("FDA") pilot opens the door for digital health devices without FDA premarket authorization to be used to provide care paid under the Center for Medicare and Medicaid Innovation ("CMMI")...more

Morris James LLP

FDA Updates Depo-Provera Label to Include Brain Tumor Risk — Key Litigation Development

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The U.S. Food and Drug Administration (FDA) has approved a significant update to the prescribing information for Depo-Provera, adding a warning about a potential association with meningiomas, a type of brain tumor. This marks...more

Butler Snow LLP

Memento Michigan Compiled Law § 600.2946(5): An Homage to Michigan’s Former Drug Immunity Law

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In 1995, the Michigan Legislature enacted its Drug Immunity Law, which provided an absolute defense for pharmaceutical companies in product liability suits stemming from the safety and efficacy of their drug products, the...more

Ropes & Gray LLP

FDA Outlines “Plausible Mechanism” Approval Pathway for Personalized Therapies, But Significant Questions Remain

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FDA Commissioner Martin Makary and Center for Biologics Evaluation and Research Director Vinay Prasad recently published an article in the New England Journal of Medicine (“NEJM”) outlining the guiding principles of a new...more

Mintz - Health Care Viewpoints

FDA in Flux — November 2025 Newsletter

Welcome to FDA in Flux — A Mintz newsletter tracking rapid changes in policy and agency actions that impact medical, life sciences, and consumer product investment decisions and development strategies....more

Katten Muchin Rosenman LLP

Unlocking Bespoke Product Approvals: FDA Puts Forth Plausible Mechanism Pathway

On November 12, 2025, the New England Journal of Medicine published an article authored by FDA Commissioner Marty Makary and Center for Biologics Evaluation and Research (CBER) Director Vinay Prasad introducing the concept of...more

Goodwin

Vera Therapeutics Submits BLA to FDA for Atacicept Fusion Protein

Goodwin on

On November 7, Vera Therapeutics announced that it submitted a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) through the Accelerated Approval Program for atacicept for the treatment of...more

Hogan Lovells

FDA Announces “plausible Mechanism” Approval Pathway for Certain Personalized Therapies, With Few Details

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Late on Wednesday, U.S. Food and Drug Administration (FDA) Commissioner Marty Makary and Center for Biologics Evaluation & Research (CBER) Director Vinay Prasad published an article in the New England Journal of Medicine...more

Foley Hoag LLP

FDA Leadership Outlines “Plausible Mechanism” Pathway for Bespoke Therapies

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Key Takeaways: The US Food and Drug Administration (FDA) is proposing a new “plausible mechanism” pathway that will enable the limited approval of bespoke therapies when randomized trials are impractical....more

Wolf, Greenfield & Sacks, P.C.

Navigating Medical Device Regulation and IP Protection in the United States (Part 1 of 2)

In the United States, medical device regulation and intellectual property (IP) protection are governed by complex statutory and regulatory frameworks that are distinct from—but closely related to, and in some cases...more

Polsinelli

New FDA Guidance Could Speed Biosimilar Approvals and Cut Costs

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Key Takeaways: The FDA released draft guidance indicating it may approve certain biosimilars without requiring a comparative efficacy study (CES), traditionally a costly and time-intensive step....more

Gardner Law

FDA Operations During the FY 2026 Government Shutdown

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With a federal government shutdown now in effect, FDA has activated its FY 2026 contingency staffing plan. While essential safety activities and user fee–funded reviews will continue, many programs including new submissions...more

Robins Kaplan LLP

ANDA Approvals - Third Quarter 2025

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This chart tracks the date, drug, reference-listed company, and applicant of Abbreviated New Drug Applications and 505(b)(2) Applications receiving final approval by the FDA....more

Jones Day

Filing Litigation to Challenge FDA Delays in NDA or BLA Review

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Though every new presidential administration creates new challenges—and opportunities—for businesses, the second Trump administration has proven to be particularly eventful for the life sciences industry. ...more

Goodwin

Recent International Biosimilar Regulatory Updates

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In the past few weeks, several biosimilar products have been granted marketing authorization in Europe and Japan, and additional products have been recommended for approval in Europe. ...more

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