Despite the current environment of social distancing, the United States Patent and Trademark Office (USPTO) has continued full operations while eliminating face-to-face interactions. For example, Patent Trial and Appeal Board (PTAB) hearings are being held via telephone or by video, and the PTAB is issuing precedential and informative decisions on a wide range of topics. This issue of The PTAB Review discusses the Supreme Court’s most recent decision about America Invents Act (AIA) trials, the PTAB’s most recent precedential and informative decisions, and the potential for estoppel with simultaneous petitions filed challenging the same claims.