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Biosimilars

Goodwin

European Biologic and Biosimilar Updates

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On January 12, 2026, Sanofi announced that the European Commission approved its Teizeild (teplizumab) for delaying progression to stage 3 type 1 diabetes (“T1D”) in adults and children eight years and older who have stage 2...more

Goodwin

Genentech/Hoffmann La-Roche and Shanghai Henlius Biotech/Organon Settle Pertuzumab BPCIA Case

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On January 30, 2026, the U.S. District Court for the District of New Jersey entered a Joint Stipulation of Dismissal resolving the pertuzumab BPCIA litigation between Genentech, Inc. and Hoffmann-La Roche Inc. (together,...more

Venable LLP

Genentech and Shanghai Henlius Biotech Settle Perjeta® Biosimilar BPCIA Litigation

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On January 30, 2026, the Court ordered Genentech / Hoffmann-La Roche and Shanghai Henlius Biotech / Organon’s stipulated dismissal of Case No. 2:25-cv-14648 (D.N.J.) due to a settlement agreement between the parties.  ...more

Alston & Bird

Biological Products Regulation Part 4: Biosimilars 101

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Welcome to Alston & Bird’s introduction to biological products regulation. In this five-part intro-level series, we provide answers to a number of questions drug developers may have about the regulation and regulatory pathway...more

Venable LLP

Shanghai Henlius Biotech Announces FDA Acceptance of aBLA for Proposed Avastin® Biosimilar HLX04

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On January 13, 2026, Shanghai Henlius Biotech announced the FDA acceptance of an aBLA for HLX04, its proposed biosimilar of Genentech’s Avastin® (bevacizumab). ...more

Rothwell, Figg, Ernst & Manbeck, P.C.

PTAB Reforms Shift the Battleground: Why Ex Parte Reexaminations Are Gaining Ground as IPRs Fade

In the evolving biosimilar landscape, patent challenges remain a critical strategy to clear the path for market entry. Recent reforms at the Patent Trial and Appeal Board (PTAB) under Director John Squires have significantly...more

Venable LLP

Dr. Reddy’s Files aBLA for Orencia® (abatacept) Biosimilar DRL_AB

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On January 21, 2026, as part of an earnings call, Dr. Reddy’s announced the filing of an aBLA for an intravenous (IV) formulation of DRL_AB (abatacept), a proposed biosimilar of Bristol-Myers Squibb’s Orencia® (abatacept) in...more

Alston & Bird

Biological Products Regulation Part 3: Unlocking Reference Product Exclusivity: What Sponsors Need to Know

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Welcome to Alston & Bird’s introduction to biological products regulation. In this five-part intro-level series, we provide answers to a number of questions drug developers may have about the regulation and regulatory pathway...more

Skadden, Arps, Slate, Meagher & Flom LLP

New FDA Approach to Drug Prices Adds Uncertainty to Drug Approval Process

In the first year of the second Trump administration, we have seen the Food and Drug Administration (FDA) take an unprecedented role in drug pricing policy....more

Venable LLP

Hikma Announces U.S. Launch of Prolia® / Xgeva® Biosimilars Enoby™ / Xtrenbo™ (denosumab-qbde)

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On January 19, 2026, Hikma announced the launch of Enoby™ / Xtrenbo™ (denosumab-qbde), biosimilars of Amgen’s Prolia® / Xgeva® (denosumab), following their FDA-approval in September 2025. ...more

Rothwell, Figg, Ernst & Manbeck, P.C.

How the U.S. Compares to Europe on Biosimilar Approvals and Products In the Pipeline – Updated January 22, 2026

Many Prolia®/Xgeva® (denosumab) biosimilars approved in 2025 by FDA and EMA. FDA grants first interchangeable status for rapid acting insulin aspart, KristyTM....more

Hogan Lovells

JPM 2026: FDA panelists prioritize faster approvals, national security, AI, and more

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Speaking at the 2026 J.P. Morgan Healthcare Conference, Hogan Lovells global regulatory partners Elizabeth Jungman and Brian Carey moderated a panel discussion with U.S. Food and Drug Administration (FDA) Deputy Chief of...more

Polsinelli

Supreme Court Grants Cert. Petition in Hikma / Amarin Skinny Labeling Case

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Key Takeaways: Supreme Court to decide if “generic version” marketing can support induced infringement claims. On Jan. 16, 2026, the Court granted Hikma’s petition for cert. in a closely watched case that could redefine...more

Goodwin

Year in Review: Top Legal Developments of 2025

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This past year contained a number of significant developments in litigation involving biologics and biosimilars. The following is a recap of the top three legal developments that we covered on the Big Molecule Watch last...more

Alston & Bird

Biological Products Regulation Part 2: What Is the Regulatory Pathway for Biological Products?

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Welcome to Alston & Bird’s introduction to biological products regulation. In this five-part intro-level series, we provide answers to a number of questions drug developers may have about the regulation and regulatory pathway...more

Alston & Bird

Biological Products Regulation Part 1: Is the Product a Biological Product?

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Welcome to Alston & Bird’s introduction to biological products regulation. In this five-part intro-level series, we provide answers to a number of questions drug developers may have about the regulation and regulatory pathway...more

Smart & Biggar

2025 highlights in Canadian life sciences IP and regulatory law

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In 2025, the Rx IP Update team at Smart & Biggar reported on a number of developments in Canadian life sciences IP and regulatory law. Highlights from 2025 are below...more

Goodwin

Year in Review: Big Deals of 2025

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As we head into what is anticipated to be a strong year for biopharma dealmaking, we look back at some of the biggest deals in 2025 that focus on biologics and biosimilars....more

Venable LLP

FDA Approves Third Lucentis® (ranibizumab) Interchangeable Biosimilar: Formycon’s Nufymco™

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On December 18, 2025, the FDA approved Formycon and Zydus’s Nufymco™ (ranibizumab-leyk) as the third interchangeable biosimilar of Genentech’s Lucentis® (ranibizumab). Lucentis® biosimilars have been on the market since July...more

Venable LLP

Denosumab Biosimilar Updates: Boncresa™ / Oziltus™ Approval, AVT03 Complete Response Letter

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On December 19, 2025, the FDA approved Amneal / mAbxience’s Boncresa™ / Oziltus™ (denosumab-mobz) as the nineth biosimilars of Amgen’s Prolia® / Xgeva® (denosumab). ...more

Venable LLP

Aflibercept Biosimilar Updates: SCD-411 FDA aBLA Acceptance; AVT06 Settlement Agreement

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On December 3, 2025, Fresenius Kabi and SamChunDang Pharm announced the FDA acceptance of their aBLA for SCD-411 (aflibercept), a proposed biosimilar of Regeneron’s EYLEA® (aflibercept). Under their licensing agreement...more

Smart & Biggar

Federal Court of Appeal confirms BYOOVIZ is confusing with Novartis’ BEOVU trademark

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On November 28, 2025, the Federal Court of Appeal (FCA) upheld an injunction against the use of the trademark BYOOVIZ for an ophthalmic biosimilar, confirming the application judge’s finding that the mark is likely to be...more

Goodwin

Celltrion and Sandoz Launch Their Aflibercept Biosimilars in Europe

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On November 27, 2025, Celltrion announced that Health Canada approved EYDENZELT® (aflibercept-boav), a biosimilar referencing Regeneron’s EYLEA® (aflibercept), in both vial and pre-filled syringe form, to treat all...more

Fish & Richardson

UK High Court Clarifies Scope of SPC Waiver Notification Requirements

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A recent judgment of the U.K. High Court (Patents Court) has clarified the scope of the notification requirements for the supplementary protection certificate (SPC) manufacturing waiver in the U.K. ...more

Goodwin

FDA Approves mAbxience and Amneal’s Denosumab Biosimilars

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On December 22, 2025, the FDA approved mAbxience and Amneal’s Biologics Licensing Applications (BLAs) for BONCRESA™ (denosumab-mobz) and OZILTUS™ (denosumab-mobz), biosimilars referencing Amgen’s PROLIA® (denosumab) and...more

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