News & Analysis as of

Abbreviated New Drug Application (ANDA)

Akin Gump Strauss Hauer & Feld LLP

District Court: Launch Date, Not ANDA Filing Used for Hypothetical Negotiation in ANDA Case

In a Hatch-Waxman case, the District of Delaware denied a motion for summary judgment seeking to apply the ANDA filing date as the date of the hypothetical negotiation used to calculate reasonable royalty damages. Instead,...more

Knobbe Martens

Life Science Update | October 2025

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Beginning on October 20, 2025, recently confirmed United States Patent and Trademark Office (USPTO) Director John A. Squires met with European Patent Office (EPO) Vice-President Steve Rowan and Japanese Patent Office (JPO)...more

Alston & Bird

Health Care Week in Review | Government Shutdown Ends; FDA Announces a Warning Label Change for Hormone Replacement Therapy (HRT)...

Alston & Bird on

Below is Alston & Bird’s Health Care Week in Review, which provides a synopsis of the latest news in health care regulations, notices, and guidance; federal legislation and congressional committee action; reports, studies,...more

Robins Kaplan LLP

New ANDA Cases - Third Quarter 2025

Robins Kaplan LLP on

This chart summarizes the case name, presiding judge, drug, and patents-at-issue in all federal district court cases that are filed pursuant to the Hatch-Waxman Act. It also includes the same information for proceedings...more

Robins Kaplan LLP

Generic Launches - Third Quarter 2025

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This chart tracks the date, drug, reference-listed company, applicant, and indications of publicly available drug launches resulting from Abbreviated New Drug Applications and 505(b)(2) Applications....more

Robins Kaplan LLP

ANDA Litigation Settlements - Third Quarter 2025

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This chart summarizes the case name, drug, patents-in-suit, and publicly available terms for reported settlements in federal district court cases that are filed pursuant to the Hatch-Waxman Act....more

Robins Kaplan LLP

ANDA Approvals - Third Quarter 2025

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This chart tracks the date, drug, reference-listed company, and applicant of Abbreviated New Drug Applications and 505(b)(2) Applications receiving final approval by the FDA....more

Robins Kaplan LLP

In re Selenious Acid Litigation

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Nature of the Case and Issue(s) Presented: Plaintiff American Regent, Inc. (“ARI”) sued multiple ANDA filers (including Sun, Cipla, RK Pharma, and Aspiro) under § 271(e)(2) of the Hatch Waxman Act, and moved for a preliminary...more

Fish & Richardson

Lessons for Biopharma From the Battle of Entresto®

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After more than six years of high-stakes litigation in multiple courts and regulatory fights at the Food and Drug Administration (FDA), generic versions of Novartis Pharmaceuticals Corp. (“Novartis”)’s Entresto® have entered...more

Robins Kaplan LLP

In re Entresto (sacubitril/valsartan) Patent Litigation (Novartis Pharms. Corp. v. MSN Pharms. Inc.)

Robins Kaplan LLP on

Nature of the Case and Issue(s) Presented: Novartis holds the NDA for Entresto, a drug used to treat heart failure, having the active ingredients sacubitril and valsartan. The ’918 patent is not an Orange Book-listed patent...more

Robins Kaplan LLP

Novo Nordisk, Inc. v. Mylan Pharms. Inc.

Robins Kaplan LLP on

Nature of the Case and Issue(s) Presented: Novo makes and sells Wegovy. Novo sued Mylan asserting patent infringement of five patents that are listed, or Novo intends to list, in FDA’s Orange Book. In its complaint, Novo...more

Robins Kaplan LLP

Radius Health, Inc. v. Orbicular Pharm. Techs. Private Ltd.

Robins Kaplan LLP on

Nature of the Case and Issue(s) Presented: Tymlos is used to treat osteoporosis. The API in Tymlos, abaloparatide, is a synthetic analog of the first 34 amino acids of parathyroid hormone related protein (“PTHrP”). Early...more

Robins Kaplan LLP

Mallinckrodt plc v. Airgas Therapeutics LLC

Robins Kaplan LLP on

Nature of the Case and Issue(s) Presented: Mallinckrodt’s (“MNK”) patents cover INOmax and its delivery system, DSIR Plus, which comprise products that administer inhaled nitric oxide gas (“iNO”) in a hospital setting to...more

Robins Kaplan LLP

Janssen Pharms., Inc. v. Teva Pharms. USA, Inc. - 2025 Q3

Robins Kaplan LLP on

Nature of the Case and Issue(s) Presented: Invega Sustenna® is a long-acting injectable antipsychotic medication indicated for the treatment of schizophrenia in adults. The ’906 patent addresses the problem of noncompliance...more

Knobbe Martens

New FDA Program Prioritizes Review of Certain ANDAs

Knobbe Martens on

On October 3, 2025, the U.S. Food and Drug Administration (FDA) unveiled a pilot prioritization program that provides for accelerated review of abbreviated new drug applications (ANDAs) for generic companies that test and...more

Katten Muchin Rosenman LLP

FDA Launches New ANDA Prioritization Pilot to Support U.S.-Based Generic Manufacturing

The U.S. Food and Drug Administration (FDA) has introduced a new pilot program to prioritize Abbreviated New Drug Applications (ANDAs) for generic drugs that utilize U.S.-based manufacturing and testing. Announced on October...more

Venable LLP

Impact of the Government Shutdown on FDA, New ANDA Prioritization Pilot Program, and FDA Holds PreCheck Meeting with Stakeholders

Venable LLP on

Through our Venable FDA Pulse series, we provide insight into key developments within the Food and Drug Administration (FDA or the Agency), emerging trends, enforcement activity, and other topics impacting stakeholders....more

Hogan Lovells

FDA PreCheck meeting weighs how more clarity may help de-risk US manufacturing investments - Agency invites additional comments on...

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At a September 30, 2025, public meeting hosted by the U.S. Food and Drug Administration (FDA), industry stakeholders expressed strong support for the newly launched FDA PreCheck Program, while raising key questions about its...more

Fish & Richardson

The Doctrine of Equivalents in Pharmaceutical Actions

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When a product or process does not literally infringe a patent’s claim language, the doctrine of equivalents (DOE) holds that a competitor’s product or process may still infringe if it is substantially equivalent to the...more

Troutman Pepper Locke

Will the Supreme Court Give Drug Manufacturers the Skinny on Induced Infringement?

Troutman Pepper Locke on

The Supreme Court may soon address a recent, pivotal case involving the use of “skinny labels” to avoid inducing infringement in pharmaceutical patent infringement cases. The outcome could clarify whether and how generic drug...more

Skadden, Arps, Slate, Meagher & Flom LLP

Life Sciences Companies Face an Array of New and Increasing Litigation Risks

In-house legal teams are encountering mounting pressure, especially as they balance cost control, risk mitigation and rising litigation of all types. For life sciences companies, the current environment raises the stakes as...more

Hogan Lovells

Court gives new life to the post-CRL administrative hearing process, rules that FDA can deny hearing only when evidence is...

Hogan Lovells on

On August 15, 2025, the U.S. Court of Appeals for the D.C. Circuit limited FDA's ability to deny a hearing on the approvability of a new drug application (NDA) based on a lack of “substantial evidence.”...more

Latham & Watkins LLP

FDA Publishes Complete Response Letters for Unapproved Drug Applications

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On September 4, 2025, the US Food and Drug Administration (FDA or the Agency) announced that it released a second batch of complete response letters (CRLs) — which explain the Agency’s determination for refusing to approve a...more

Orrick, Herrington & Sutcliffe LLP

FDA’s “Radical Transparency” Arrives: Real-Time Publication of CRLs Poses New Exposures for Innovative Pharmaceutical Companies

The U.S. Food and Drug Administration (FDA) has unveiled a sweeping transparency initiative that will fundamentally change how innovative drug and biologic developers interface with the Agency and the market. ...more

Proskauer - The Patent Playbook

Novo Nordisk v. Mylan: Method of Treatment Claims Must Be Aligned with Label

Method-of-treatment (“MoT”) claims can be powerful tools for pharmaceutical companies seeking to extend market exclusivity for their products after the original composition-of-matter patents expire. However, the District of...more

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